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Dihydro Donepezil

Dihydro Donepezil

Item no.	HY-131252-10mg
Manufacturer	MedChem Express
CASRN	120012-04-6
Amount	10 mg
Quantity options	100 mg 10 mg 1 ea 250 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Ogura, H., et al., Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find Exp Clin Pharmacol, 2000. 22(8): p. 609-13.
Smiles	OC1C(CC2CCN(CC3=CC=CC=C3)CC2)CC4=C1C=C(OC)C(OC)=C4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Dihydro E2020
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Cholinesterase (ChE)
Shipping Temperature	Room temperature
Molecular Weight	381.51
Product Description	Dihydro Donepezil (Dihydro E2020) is a metabolite of Donepezil. Donepezil is a specific and potent AChE inhibitor with IC 50 s of 8.12 nM and 11.6 nM for bAChE and hAChE , respectively [1] .
Manufacturer - Research Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Neuronal Signaling
Isoform	AChE
Clinical information	No Development Reported

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