Comparison

MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin European Partner

Item no. HY-132158-25mg
Manufacturer MedChem Express
CASRN 2414594-29-7
Amount 25 mg
Quantity options 100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Purity 96.00
Citations [1]Li W, et, al. Synthesis and Evaluation of Camptothecin Antibody-Drug Conjugates. ACS Med Chem Lett. 2019 Sep 6;10(10):1386-1392.
Smiles O=C(C=CC1=O)N1CCCCCC(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(NCOCC(NCC2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C=C62)=O)=O)=O)=O)=O
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Shipping Condition Cool pack
Available
Manufacturer - Type
ADC Related
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
Drug-Linker Conjugates for ADC
Shipping Temperature
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Molecular Weight
902.92
Product Description
MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), a camptothecin payload, can be conjugated to a monoclonal antibody (mAb) for the synthesis of camptothecin antibody-drug conjugate (ADC)[1].
Manufacturer - Research Area
Cancer
Solubility
10 mM in DMSO
Manufacturer - Pathway
Antibody-drug Conjugate/ADC Related
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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