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YB-0158

YB-0158

Item no.	HY-136541-1mg
Manufacturer	MedChem Express
CASRN	1144043-83-3
Amount	1 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.80
Citations	[1]Masibag AN, Bergin CJ, Haebe JR, et al. Pharmacological targeting of Sam68 functions in colorectal cancer stem cells. iScience. 2021;24(12):103442.
Smiles	O=P(O[Na])(O[Na])OC1=CC=C(C[C@H]2C(N(CC3=CC=CC4=C3NN=C4)C[C@H](N(C(NCC5=CC=CC=C5)=O)N(CC=C)C6)N2C6=O)=O)C=C1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Wnt pathway inhibitor 2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Wnt
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	703.59
Product Description	YB-0158 (Wnt pathway inhibitor 2) is a reverse-turn peptidomimetic and a potent colorectal cancer stem cell (CSC) targeting agent. YB-0158 disrupts Sam68-Src interactions and induces apoptosis in CRC cells. Anti-cancer activities[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)\|H2O: < 0.1 mg/mL (ultrasonic; adjust pH to 1 with 1M HCl)
Manufacturer - Pathway	Apoptosis; Stem Cell/Wnt
Clinical information	No Development Reported

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HY-136541-1mg-safety-datasheet.pdf