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KRAS G12D inhibitor 10

KRAS G12D inhibitor 10

Item no.	HY-143603-50mg
Manufacturer	MedChem Express
CASRN	2648551-54-4
Amount	50 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1] Jennifer PITZEN, et al. Covalent ras inhibitors and uses thereof. Patent WO2021108683A1.
Smiles	O=C(N1[C@@H](CC#N)CN(C2=C3C(CN(C4=C5C(C)=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(C)CCC6)=N2)CC1)NCCCl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Ras
Shipping Temperature	Room temperature
Molecular Weight	617.18
Product Description	KRAS G12D inhibitor 10 is a potent inhibitor of KRAS G12D. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 10 has the potential for the research of KRAS G12D-mediated cancer (extracted from patent WO2021108683A1, compound 34)[1].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	GPCR/G Protein; MAPK/ERK Pathway
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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