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Purmorphamine

Purmorphamine

Item no.	HY-15108-250mg
Manufacturer	MedChem Express
CASRN	483367-10-8
Amount	250 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 250 mg 25 mg 50 mg 5 mg
Category	Neuroscience Neural Lineage Markers Neural Transcription Factors Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.9
Citations	Arthritis Res Ther. 2024 Jan 25;26(1):36. Biochem Biophys Res Commun. 12 August 2021. Burns Trauma. 2019 Sep 23;7:29. Cancer Med. 2018 Nov;7(11):5704-5715. Int J Mol Sci. 2024 Apr 9, 25(8), 4138. J Exp Clin Cancer Res. 2018 Nov 27;37(1):287. Med Oncol. 2021 Mar 17;38(4):41. Mil Med Res. 2020 Nov 1;7(1):52. Mil Med Res. 2020 Sep 6;7(1):42. Oncol Lett. 2019 Sep;18(3):3081-3091. Patent. US20180263995A1. Pharmacol Res. 2021 Jan 26;105460. Transl Neurodegener. 2024 Oct 29;13(1):53. Life Sci. 2023 Jul 29;329:121990. [1]Beloti MM, et al. Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cells. Cell Biol Int. 2005 Jul;29(7):537-41.. . . . [2]Gu D, et al. A role for transcription factor STAT3 signaling in oncogene smoothened-driven carcinogenesis. J Biol Chem. 2012 Nov 2;287(45):38356-66. [3]Beloti MM, et al. Purmorphamine enhances osteogenic activity of human osteoblasts derived from bone marrow mesenchymal cells. Cell Biol Int. 2005 Jul;29(7):537-41.
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Autophagy; Organoid; Smo
Shipping Temperature	Room Temperature
Product Description	Purmorphamine is a smoothened/Smo receptor agonist with an EC50 of 1 μM.
Manufacturer - Research Area	Neurological Disease; Cancer
Solubility	DMSO : 33.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Autophagy; Stem Cell/Wnt
Clinical information	No Development Reported

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HY-15108-250mg-safety-datasheet.pdf