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2′-C-Methyl-6-O-methylinosine

2′-C-Methyl-6-O-methylinosine

Item no.	HY-154017-10mg
Manufacturer	MedChem Express
CASRN	565450-78-4
Amount	10 mg
Quantity options	10 mg 1 ea 1 mg 25 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Virág L, Szabó C. Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death. FASEB J. 2001 Jan;15(1):99-107.\|[2]Saugstad OD. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatr Res. 1988 Feb;23(2):143-50.
Smiles	OC[C@@H]1[C@@H](O)[C@](O)(C)[C@H](N2C(N=CN=C3OC)=C3N=C2)O1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Oligonucleotides
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Nucleoside Antimetabolite/Analog
Shipping Temperature	Room temperature
Molecular Weight	296.28
Product Description	2′-C-Methyl-6-O-methylinosine is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia [1] [2] .
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Cell Cycle/DNA Damage
Clinical information	No Development Reported

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