Comparison

2′-C-Methyl-6-O-methylinosine European Partner

Item no. HY-154017-10mg
Manufacturer MedChem Express
CASRN 565450-78-4
Amount 10 mg
Quantity options 10 mg 1 ea 1 mg 25 mg 5 mg
Category
Type Inhibitors
Specific against other
Citations [1]Virág L, Szabó C. Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death. FASEB J. 2001 Jan;15(1):99-107.|[2]Saugstad OD. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatr Res. 1988 Feb;23(2):143-50.
Smiles OC[C@@H]1[C@@H](O)[C@](O)(C)[C@H](N2C(N=CN=C3OC)=C3N=C2)O1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Room temperature
Available
Manufacturer - Type
Oligonucleotides
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
Nucleoside Antimetabolite/Analog
Shipping Temperature
Room temperature
Molecular Weight
296.28
Product Description
2′-C-Methyl-6-O-methylinosine is a hypoxanthine analog. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia [1] [2] .
Manufacturer - Research Area
Cancer
Solubility
10 mM in DMSO
Manufacturer - Pathway
Cell Cycle/DNA Damage
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
available

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