Comparison

CHBO4 European Partner

Item no. HY-155137-10mg
Manufacturer MedChem Express
CASRN 98991-32-3
Amount 10 mg
Quantity options 100 mg 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Citations [1]Thomas Parambi DG, et al. Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study. Comput Biol Chem. 2023 Aug;105:107899.
Smiles BrC1=CC=C(C(/C=C/C2=CC=C(F)C=C2)=O)C=C1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Neuroscience-Neurodegeneration
Manufacturer - Targets
Monoamine Oxidase; Reactive Oxygen Species
Shipping Temperature
Room temperature
Molecular Weight
305.14
Product Description
CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC 50 value of 0.031 μM in CHBO subseries and an K i value of 0.010 ± 0.005 μM. CHBO4 reduce cell damage by scavenging intracellular reactive oxygen species ( ROS ). CHBO4 can be used for Parkinson's Disease (PD) research [1] .
Manufacturer - Research Area
Neurological Disease
Solubility
10 mM in DMSO
Manufacturer - Pathway
Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Isoform
MAO-B
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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