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10-Deacetylbaccatin III

10-Deacetylbaccatin III

Item no.	HY-16565-1g
Manufacturer	MedChem Express
CASRN	32981-86-5
Amount	1 g
Quantity options	100 mg 10 mM/1 mL 1 g 200 mg 500 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.80
Citations	[1]Li S, Zhang P, Zhang M, Fu C, Yu L. Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biol (Stuttg). 2013 Jan;15(1):19-26.\|[2]Naill MC, Kolewe ME, Roberts SC. Paclitaxel uptake and transport in Taxus cell suspension cultures. Biochem Eng J. 2012 Apr 15;63:50-56.\|[3]Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res. 2012 Apr;26(4):552-6.\|[4]Kevin Walker and Rodney Croteau. Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli. PNAS, 2000 , 97（25）：13591-13596.\|[5]Georgopoulou K, et al. In Vitro Activity of 10-Deacetylbaccatin III against Leishmania donovani Promastigotes and Intracellular Amastigotes. Planta Med, 2007, 73(11):1081-1088. \|[6]Patel R N et al. Enzymatic acetylation of 10-deacetylbaccatin III to baccatin III by C-10 deacetylase from Nocardioides luteus SC 13913. Enzyme and Microbial Technology, 2000, 27(5):371-375.
Smiles	CC1=C([C@@H](O)C([C@@]2(C)[C@@]3([H])[C@@](CO4)(OC(C)=O)[C@@]4([H])C[C@@H]2O)=O)C(C)(C)[C@@]([C@H]3OC(C5=CC=CC=C5)=O)(O)C[C@@H]1O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Biochemical Assay Reagents; Drug Intermediate; Parasite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	544.59
Product Description	10-Deacetylbaccatin-III is an intermediate in the preparation process of paclitaxel. 10-Deacetylbaccatin III can be isolated from the dried needles and small branches of the European yew tree (Taxus baccata). 10-Deacetylbaccatin III exhibits antileishmanial activity[1][2][3][4][5][6].
Manufacturer - Research Area	Infection
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Others
Clinical information	No Development Reported

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HY-16565-1g-safety-datasheet.pdf