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Adrenosterone

Adrenosterone

Item no.	HY-17462-1g
Manufacturer	MedChem Express
CASRN	382-45-6
Amount	1 g
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg 5 g
Category	Metabolism Glucose Homeostasis Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.97
Citations	[1]Brooker L, et al. Carbon isotope ratio analysis of endogenous glucocorticoid urinary metabolites after cortisone acetate andadrenosterone administration for doping control. Drug Test Anal. 2012 Dec;4(12):951-61.\|[2]Choudhary MI, et al. Biotransformation of adrenosterone by filamentous fungus, Cunninghamella elegans. Steroids. 2007 Dec;72(14):923-9.\|[3]Joji Nakayama, et al. A Novel Zebrafish Model of Metastasis Identifies the HSD11β1 Inhibitor Adrenosterone as a Suppressor of Epithelial-Mesenchymal Transition and Metastatic Dissemination. Mol Cancer Res. 2020 Mar;18(3):477-487.
Smiles	C[C@@]([C@](CC1)([H])[C@]2([H])CCC3=CC(CC[C@]3(C)[C@@]2([H])C4=O)=O)(C4)C1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(+)-Adrenosterone
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Androgen Receptor; Endogenous Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	300.39
Product Description	Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor.Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells[1][2][3].
Manufacturer - Research Area	Cancer; Endocrinology
Solubility	DMSO: 31.25 mg/mL (ultrasonic; warming; heat to 80°C)
Manufacturer - Pathway	Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Isoform	Human Endogenous Metabolite
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-17462-1g-safety-datasheet.pdf