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Metoprolol

Metoprolol

Item no.	HY-17503-10mM
Manufacturer	MedChem Express
CASRN	51384-51-1
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 25 mg 50 mg
Category	Cardiovascular Research Heart Failure Myocardial Infarction Hypertension Inhibitors & Compound Libraries Small Molecules Arrhythmias
Type	Inhibitors
Specific against	other
Purity	99.97
Citations	[1]Ulleryd MA, et al. Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. Biomed Res Int. 2014;2014:548783.\|[2]Wang D, et al. Carvedilol has stronger anti-inflammation and anti-virus effects than metoprolol in murine model with coxsackievirus B3-induced viral myocarditis. Gene. 2014 Sep 1;547(2):195-201.\|[3]Hajatbeigi B, et al. Cytotoxicity of Metoprolol on Leukemic Cells in Vitro. IJBC 2018; 10(4): 124-129.\|[4]Su Q, et al. Effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization in rats. Exp Clin Cardiol. 2013 Spring;18(2):161-5. Chemosphere. 2019 Jun;225:378-387. \|Clin Pharmacol Ther. 2023 Nov 16.\|Environ Toxicol. 2023 Dec 2.\|Int Immunopharmacol. 2024 Aug 9:140:112894.\|J Chromatogr B. 2023 Jun 20, 123804.\|J Intern Med. 2024 Jul 29.\|J Pharmaceut Biomed. 2020, 113870.\|Preprints. 2023 Jun 19.\|SSRN. 2024 May 30.\|bioRxiv. 2024 Mar 29.\|PLoS One. 2024 Aug 14;19(8):e0301875.\|Eur J Med Chem. 2024 Dec 5.\|iScience. 2025 Jan 17;28(2):111831.\|J Pharmacol Sci. 2020 Sep;144(1):30-42.
Smiles	OC(CNC(C)C)COC1=CC=C(CCOC)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Adrenergic Receptor; Apoptosis
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	267.36
Product Description	Metoprolol is an orally active, selective β1-adrenoceptor antagonist. Metoprolol shows anti-inflammation, antitumor and anti-angiogenic properties[1][2][3].
Manufacturer - Research Area	Cancer; Infection; Endocrinology; Cardiovascular Disease
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; GPCR/G Protein; Neuronal Signaling
Isoform	β adrenergic receptor
Clinical information	Launched

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HY-17503-10mM-safety-datasheet.pdf