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SBI-0640756

SBI-0640756

Item no.	HY-19560-100mg
Manufacturer	MedChem Express
CASRN	1821280-29-8
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 2 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Skin Cancer
Type	Inhibitors
Specific against	other
Purity	99.75
Citations	[1]Feng Y et al. SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex. Cancer Res, 2015 Dec 15, 75(24):5211-8.
Smiles	O=C1C(C(/C=C/C2=CC(F)=CN=C2)=O)=C(C3=CC=CC=C3)C4=C(C=CC(Cl)=C4)N1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	SBI-756
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Autophagy; Eukaryotic Initiation Factor (eIF)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	404.82
Product Description	SBI-0640756 (SBI-756) is an inhibitor of eIF4G1 and disrupts the eIF4F complex.
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 26 mg/mL
Manufacturer - Pathway	Autophagy; Cell Cycle/DNA Damage
Isoform	eIF4
Clinical information	No Development Reported

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HY-19560-100mg-safety-datasheet.pdf