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Fluoxetine (hydrochloride)

Fluoxetine (hydrochloride)

Item no.	HY-B0102A-10mg
Manufacturer	MedChem Express
CASRN	56296-78-7
Amount	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 500 mg 50 mg 5 mg
Category	Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.97
Citations	[1]Malberg JE, et al. Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology. 2003 Sep;28(9):1562-71\|[2]Kodama M, et al. Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat. Biol Psychiatry. 2004 Oct 15;56(8):570-80.\|[3]Wang JW, et al. Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. J Neurosci. 2008 Feb 6;28(6):1374-84.\|[4]Bymaster FP, et al. Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. Psychopharmacology (Berl). 2002 Apr;160(4):353-61\|[5]Zhang W, et al. Synergistic effects of olanzapine and other antipsychotic agents in combination with fluoxetine on norepinephrine and dopamine release in rat prefrontal cortex. Neuropsychopharmacology. 2000 Sep;23(3):250-62.\|[6]Su WJ, et al. Antidiabetic drug glyburide modulates depressive-like behavior comorbid with insulin resistance. J Neuroinflammation. 2017 Oct 30;14(1):210. Fundam Clin Pharmacol. 2018 Aug;32(4):363-377.\|J Neuroinflammation. 2017 Oct 30;14(1):210.\|J Neuroinflammation. 2023 May 10;20(1):112.\|Neuropharmacology. 2021 Feb 15;184:108410.\|Neurotox Res. 2020 Dec;38(4):887-899.\|Preprints. 2023 Dec 27.\|World J Biol Psychiatry. 2024 Nov 29:1-18.\|Behav Brain Res. 2017 Jan 15;317:62-70. \|Behav Pharmacol. 2021 Jan 6.\|Behav Pharmacol. 2024 Apr 24.\|Behav Pharmacol. 2024 Dec 2.\|Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868.\|Biochem Pharmacol. 2023 Oct 5:115846.\|Biomedicines. 2023 Apr 26, 11(5), 1279.\|Brain Behav Immun. 2021 Mar 15;S0889-1591(21)00114-8.\|Cell Prolif. 2021 Jan;54(1):e12953.\|Cell Rep. 2021 Nov 2;37(5):109957.\|Chemosphere. 2019 Jun;225:378-387. \|Eur J Pharmacol. 2019 Jan 15;843:260-267.\|J Clin Psychopharmacol. 2021 Jun 11.\|J Psychiatr Res. 2023 Oct 19.\|J Transl Med. 2024 Aug 22;22(1):785.\|Nat Med. 2019 Sep;25(9):1428-1441.\|Orebro University. 2024.\|Prog Neuropsychopharmacol Biol Psychiatry. 2017 Jun 15;79(Pt B):258-267.\|Reprod Toxicol. 2025 Jan 16:108840.\|Research Square Preprint. 2023 Jun 16.\|Research Square Preprint. 2023 Jun 29.\|Research Square Preprint. 2024 Dec 16.\|Virol J. 2024 Aug 8;21(1):181.
Smiles	FC(C1=CC=C(OC(C2=CC=CC=C2)CCNC)C=C1)(F)F.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	LY 110140
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Autophagy; Serotonin Transporter
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	345.79
Product Description	Fluoxetine hydrochloride (LY 110140) is an antidepressant and a selective serotonin reuptake inhibitor.
Manufacturer - Research Area	Neurological Disease; Cancer
Solubility	DMSO: ≥ 25 mg/mL\|H2O: 8.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Autophagy; Neuronal Signaling
Clinical information	Launched

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Amount: 10 mg

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