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Cloxiquine

Cloxiquine

Item no.	HY-B0963-10g
Manufacturer	MedChem Express
CASRN	130-16-5
Amount	10 g
Quantity options	100 g 10 g 10 mM/1 mL 25 g 500 mg 50 g 5 g
Category	Oncology By Cell Type Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.94
Citations	[1]Latosińska JN, et al. Supramolecular synthon pattern in solid clioquinol and cloxiquine (APIs of antibacterial, antifungal, antiaging and antituberculosis drugs) studied by <sup>35</sup>Cl NQR, <sup>1</sup>H-<sup>17</sup>O and <sup>1</sup>H-<sup>14</sup>N NQDR and DFT/QTAIM. J Mol Model. 2011 Jul;17(7):1781-800.\|[2]Zhang W, et, al. Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ. Cell Death Dis. 2019 May 28;10(6):404.\|[3]Hongmanee P, et, al. In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2007 Mar;51(3):1105-6.
Smiles	OC1=C2N=CC=CC2=C(Cl)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	5-Chloro-8-quinolinol
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Bacterial; Fungal; Parasite; PPAR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	179.61
Product Description	Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ[1][2].
Manufacturer - Research Area	Cancer; Infection
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Isoform	Amebae
Clinical information	No Development Reported

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HY-B0963-10g-safety-datasheet.pdf