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Deoxyarbutin

Deoxyarbutin

Item no.	HY-B1461-25g
Manufacturer	MedChem Express
CASRN	53936-56-4
Amount	25 g
Quantity options	100 g 100 mg 10 g 10 mM/1 mL 1 g 25 g 500 mg 50 g 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.92
Citations	[1]Boissy RE, et al. DeoxyArbutin: a novel reversible tyrosinase inhibitor with effective in vivo skin lightening potency. Exp Dermatol. 2005 Aug;14(8):601-8. \|[2]Ma L, et al. Deoxyarbutin displays antitumour activity against melanoma in vitro and in vivo through a p38-mediated mitochondria associated apoptotic pathway. Sci Rep. 2017 Aug 3;7(1):7197. \|[3]Li Y, et al. Deoxyarbutin attenuates severe acute pancreatitis via the HtrA2/PGC-1α pathway. Free Radic Res. 2022 Sep-Oct;56(9-10):651-665.
Smiles	OC1=CC=C(OC2CCCCO2)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-sugar/lipid metabolism
Manufacturer - Targets	Apoptosis; Tyrosinase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	194.23
Product Description	Deoxyarbutin is an orally active tyrosinase inhibitor that can promote apoptosis of melanoma cells, enhance the vitality of mouse acinar cells, and has skin whitening and anti-tumor activity[1][2][3].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-B1461-25g-safety-datasheet.pdf