L-Methionine-DL-sulfoximine

Reference compound

Glutaminase

-20°C, 3 years; 4°C, 2 years (Powder)

L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS) , is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS) [1] [2] [3] [4] [5] .

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)|H2O : 50 mg/mL (ultrasonic)

No Development Reported