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Cinchonidine

Cinchonidine

Item no.	HY-N0173-1g
Manufacturer	MedChem Express
CASRN	485-71-2
Amount	1 g
Quantity options	100 g 100 mg 10 g 10 mM/1 mL 1 g 25 g 500 mg 50 g 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.62
Citations	[1]Beckman ML, et al. Stereoselective inhibition of serotonin transporters by antimalarial compounds. Neurochem Int. 2014 Jul;73:98-106.
Smiles	C=C[C@H]1C[N@](CC[C@H]1C2)[C@]2([H])[C@H](O)C3=CC=NC4=CC=CC=C34
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	α-Quinidine
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Parasite; Serotonin Transporter
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light, stored under nitrogen)
Molecular Weight	294.40
Product Description	Cinchonidine (α-Quinidine) is a cinchona alkaloid found in Cinchona officinalis and Gongronema latifolium. A building block used in asymmetric synthesis in organic chemistry. Weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Antimalarial activities[1].
Manufacturer - Research Area	Infection
Solubility	DMSO: 33.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Neuronal Signaling
Isoform	Plasmodium
Clinical information	No Development Reported

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HY-N0173-1g-safety-datasheet.pdf