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Sinapaldehyde

Sinapaldehyde

Item no.	HY-N1312-10mM
Manufacturer	MedChem Express
CASRN	4206-58-0
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 250 mg 50 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Lung Cancer
Type	Inhibitors
Specific against	other
Purity	99.96
Citations	[1]Waranya Lakornwong, et al. A New Coruleoellagic Acid Derivative From Stems of <i>Rhodamnia Dumetorum</i>. Nat Prod Res. 2018 Jul;32(14):1653-1659.\|[2]Baek SH, et al. Anti-Inflammatory Activity and ROS Regulation Effect of Sinapaldehyde in LPS-Stimulated RAW 264.7 Macrophages. Molecules. 2020 Sep 7;25(18):4089.
Smiles	O=C/C=C/C1=CC(OC)=C(O)C(OC)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Bacterial; COX; Interleukin Related; JNK; NO Synthase; PERK; Reactive Oxygen Species (ROS)
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	208.21
Product Description	Sinapaldehyde is a methoxyphenol and a selective COX-2 inhibitor (IC50: 47.8 µM) that can be extracted from various plants. Sinapaldehyde has antibacterial, anti-inflammatory, and antioxidant activities. Sinapaldehyde can scavenge DPPH free radicals (IC50: 172 μM). Sinapaldehyde is active against both Gram-negative and Gram-positive bacteria[1][2].
Manufacturer - Research Area	Infection; Inflammation/Immunology
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB
Isoform	COX-2; IL-6
Clinical information	No Development Reported

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HY-N1312-10mM-safety-datasheet.pdf