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Agaric acid

Agaric acid

Item no.	HY-N4104-10mM
Manufacturer	MedChem Express
CASRN	666-99-9
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.45
Citations	[1]García N, et al. Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Its dependence on membrane fluidity. Mitochondrion. 2005 Aug;5(4):272-81.\|[2]Freedland RA, et al. Agaric acid. Methods Enzymol. 1981;72:497-506.\|[3]Lories B, et al. Agaric acid reduces Salmonella biofilm formation by inhibiting flagellar motility. Biofilm. 2020 May 29;2:100022.\|[4]Chávez E, et al. The effect of agaric acid on citrate transport in rat liver mitochondria. Life Sci. 1978 Oct 9;23(14):1423-9.
Smiles	CCCCCCCCCCCCCCCCC(C(O)=O)C(C(O)=O)(O)CC(O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Agaricinic Acid
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-sugar/lipid metabolism
Manufacturer - Targets	Bacterial; Calcium Channel; Mitochondrial Metabolism
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	416.55
Product Description	Agaric acid (Agaricinic Acid) is an orally active inhibitor of adenine nucleotide translocase found in specific fungi. Agaric acid can inhibit the biofilm formation of various bacteria such as Salmonella. Agaric acid can also induce mitochondrial permeability transition, prompting mitochondria to release Ca2+, disrupting the transmembrane potential, and causing mitochondrial swelling. In addition, Agaric acid can also inhibit citrate transport in liver mitochondria and participate in the inhibition of fatty acid synthesis, affecting multiple metabolic processes[1][2][3][4].
Manufacturer - Research Area	Infection; Metabolic Disease
Solubility	DMSO: 125 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Clinical information	No Development Reported

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HY-N4104-10mM-safety-datasheet.pdf