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Fmoc-8-amino-3,6-dioxaoctanoic acid

Fmoc-8-amino-3,6-dioxaoctanoic acid

Item no.	HY-W007713-5g
Manufacturer	MedChem Express
CASRN	166108-71-0
Amount	5 g
Quantity options	100 mg 10 g 10 mMx1 mL 1 g 25 g 500 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.98
Citations	[1]Nakamura A, et al. Chemogenetic Control of Protein Anchoring to Endomembranes in Living Cells with Lipid-Tethered Small Molecules. Biochemistry. 2020 Jan 21;59(2):205-211.
Smiles	O=C(O)COCCOCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Fmoc-NH-PEG2-CH2COOH
Shipping Condition	Room temperature
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	ADC Linker; PROTAC Linkers
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	385.41
Product Description	Fmoc-8-amino-3, 6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-8-amino-3, 6-dioxaoctanoic acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 25 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related; PROTAC
Isoform	Alkyl/ether Linkers; Cleavable Linker; PEG Linkers
Clinical information	No Development Reported

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HY-W007713-5g-safety-datasheet.pdf