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2,4-Di-tert-butylphenol

2,4-Di-tert-butylphenol

Item no.	HY-W014589-10mM
Manufacturer	MedChem Express
CASRN	96-76-4
Amount	10 mM/1 mL
Quantity options	100 g 10 mM/1 mL 500 g 500 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.97
Citations	[1]Zhao F, et al. Natural sources and bioactivities of 2, 4-di-tert-butylphenol and its analogs[J]. Toxins, 2020, 12(1): 35.\|[2]Ren XM, et al. 2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors. Endocrinology. 2023 Feb 11;164(4):bqad021.\|[3]Choi SJ, et al. 2,4-Di-tert-butylphenol from sweet potato protects against oxidative stress in PC12 cells and in mice. J Med Food. 2013 Nov;16(11):977-83.
Smiles	OC1=CC=C(C(C)(C)C)C=C1C(C)(C)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2,4-DTBP
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Amyloid-β; Apoptosis; Endogenous Metabolite; Fungal; RAR/RXR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	206.33
Product Description	2, 4-Di-tert-butylphenol (2, 4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2, 4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2, 4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2, 4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances[1][2][3].
Manufacturer - Research Area	Cancer; Infection; Inflammation/Immunology; Neurological Disease
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Apoptosis; Metabolic Enzyme/Protease; Neuronal Signaling; Vitamin D Related/Nuclear Receptor
Isoform	Human Endogenous Metabolite; RXRα
Clinical information	No Development Reported

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HY-W014589-10mM-safety-datasheet.pdf