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Phthalide

Phthalide

Item no.	HY-W015820-25g
Manufacturer	MedChem Express
CASRN	87-41-2
Amount	25 g
Quantity options	100 g 10 g 10 mM/1 mL 1 g 25 g 500 mg 50 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.95
Citations	[1]Liu Zeng Chen, et al. Novel phthalide derivatives: Synthesis and anti-inflammatory activity in vitro and in vivo. Eur J Med Chem. 2020 Nov 15;206:112722.\|[2]Chakapong Intaraudom, et al. Antimicrobial drimane - phthalide derivatives from Hypoxylon fendleri BCC32408. Fitoterapia. 2019 Oct;138:104353.\|[3]Xin Fang, et al. Synthesis of phthalide derivatives and evaluation on their antiplatelet aggregation and antioxidant activities. J Asian Nat Prod Res. 2020 Dec;22(12):1176-1187.\|[4]Liu X, et al. Six Phthalides as Potent Modulators of the Blood Tumor Barrier Increase the Transmembrane Transport of Compatible Compounds Via Transcellular and Paracellular Pathways. Pharmaceutical Chemistry Journal, 2024, 57(12): 1967-1976.
Smiles	O=C1OCC2=C1C=CC=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Bacterial; Biochemical Assay Reagents
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	134.13
Product Description	Phthalide is a chemical scaffold. Phthalide can be used to synthesize a variety of phthalide derivatives including anti-inflammatory agent, antimicrobial, antioxidant and blood-tumor barrier modulators[1][2][3][4].
Manufacturer - Research Area	Cancer; Infection; Inflammation/Immunology; Cardiovascular Disease
Solubility	DMSO: 100 mg/mL (ultrasonic)\|H2O: 2 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Anti-infection; Others
Clinical information	No Development Reported

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HY-W015820-25g-safety-datasheet.pdf