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DOTA-tri(t-butyl ester)

DOTA-tri(t-butyl ester)

Item no.	HY-W034551-50g
Manufacturer	MedChem Express
CASRN	137076-54-1
Amount	50 g
Quantity options	100 g 100 mg 10 g 10 mM/1 mL 1 g 25 g 25 mg 500 mg 50 g 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.46
Citations	[1]Kaneshiro TL, et, al. Synthesis and evaluation of globular Gd-DOTA-monoamide conjugates with precisely controlled nanosizes for magnetic resonance angiography. Biomacromolecules. 2008 Oct;9(10):2742-8.\|[2]Sosabowski JK, et al. Conjugation of DOTA-like chelating agents to peptides and radiolabeling with trivalent metallic isotopes. Nat Protoc. 2006;1(2):972-6.
Smiles	CC(C)(OC(CN1CCN(CC(O)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CC1)=O)C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Radionuclide-Drug Conjugates (RDCs)
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light, stored under nitrogen)
Molecular Weight	572.73
Product Description	DOTA-tri(t-butyl ester) belongs to the DOTA class of chelating agents. DOTA-tri(t-butyl ester) is a key raw material for synthesizing nanospherical magnetic resonance imaging (MRI) contrast agents, which are used in MR angiography and tumor angiogenesis imaging[1][2].
Manufacturer - Research Area	Others; Cancer
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related
Isoform	RDC Bifunctional Chelator
Clinical information	No Development Reported

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HY-W034551-50g-safety-datasheet.pdf