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BRD6989

BRD6989

Item no.	TMO-T14778-10mM
Manufacturer	TargetMol
CASRN	642008-81-9
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	CC1CCc2nc(N)c(C#N)c(-c3cccnc3)c2C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	IL Receptor\|\|\|Interleukin\|\|\|CDK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	264.33
Description	BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM.
Pathways	Cell Cycle/Checkpoint\|\|\|Immunology/Inflammation

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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