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N-Oleoyl-L-Serine

N-Oleoyl-L-Serine

Item no.	TMO-T36065-200mg
Manufacturer	TargetMol
CASRN	107743-37-3
Amount	200 mg
Quantity options	100 mg 10 mg 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	N([C@H](C(O)=O)CO)C(CCCCCCC/C=C\CCCCCCCC)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	N-Oleoylserine
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis
Storage Conditions	-20
Molecular Weight	369.54
Description	N-Oleoyl-L-Serine (N-Oleoylserine) is an endogenous long-chain fatty acid amide that is a lipid modulator of bone remodeling and stimulates osteoclast apoptosis which can be used to study osteoporosis. N-Oleoyl-L-Serine showed high activity in an osteoblast proliferation assay.N-Oleoyl-L-Serine promotes osteoclast apoptosis by inhibiting Erk1/2 phosphorylation and expression of nuclear κB ligand (RANKL) receptor activator in bone marrow stromal cells and osteoblasts, which attenuates osteoclast populations.
Pathways	Apoptosis

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 mg

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