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ICCB-19 hydrochloride

ICCB-19 hydrochloride

Item no.	TMO-T8931L-10mM
Manufacturer	TargetMol
CASRN	1803605-68-6
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	Cl.O=C(CSC1=NCCN1)NC1CCCCCC1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ICCB-19 HCl(750621-52-4 free base)
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|Autophagy\|\|\|RIP kinase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	291.84
Description	ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the N-terminal TRAF2-binding domain of TRADD (TRADD-N), which interacts with the C-terminal domain (TRADD-C) and TRAF2 to modulate the ubiquitination of RIPK1 and beclin 1.
Pathways	NF-κB\|\|\|Autophagy\|\|\|Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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