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Necrostatin-34

Necrostatin-34

Item no.	TMO-T9095-500mg
Manufacturer	TargetMol
CASRN	375835-43-1
Amount	500 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	Cc1ccc(cc1)C1CC(=O)NC(SCC(=O)Nc2nccs2)=C1C#N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4
Shipping Condition	Cool pack
Available
Manufacturer - Targets	RIP kinase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	384.48
Description	Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1, 4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.
Pathways	NF-κB\|\|\|Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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