Nimbin

Item no.	TMO-TN4659-5mg
Manufacturer	TargetMol
CASRN	5945-86-8
Amount	5 mg
Quantity options	10 mg 1 mL 1 mg 500 ug 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	COC(=O)C[C@H]1[C@@]2(C)[C@H](O[C@@H]3C[C@H](C(C)=C23)c2ccoc2)[C@H](OC(C)=O)C2[C@@](C)(C=CC(=O)[C@]12C)C(=O)OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	COX
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	540.6
Description	Nimbin is an anti-pyretic, can be used to treat arthritis, hypoglycaemia, peptic ulcers, anti-secretory activity, and it can also be used as an antibiotic. Nimbin requires to elicit a 50% inhibition of this steroid hydroxylase activity in the three insect species examined ranged from approximately 2 x 10(-5) to 1 x 10(-3). Nimbin also shows anti-feedant activity and toxicity against larvae of three species of Lepidoptera, Spodoptera littoralis (Boisd), Spodoptera frugiperda (FE Smith) and Helicoverpa armigera (Hübner) and nymphs of the locusts Schistocerca gregaria (Forskå l) and Locusta migratoria (L).
Pathways	Immunology/Inflammation\|\|\|Neuroscience

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