Comparison

Cyclic(YCDGFYACYMDV) European Partner

Item no. TMO-TP3053-10mg
Manufacturer TargetMol
CASRN 535959-77-4
Amount 10 mg
Quantity options 10 mg 10 mg 50 mg 50 mg
Category
Type Molecules
Specific against other
Smiles [C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)CC(O)=O)=O)CCSC)=O)NC(=O)[C@H]2NC(=O)[C@H](C)NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC([C@H](CC5=CC=C(O)C=C5)N)=O)CSSC2
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Shipping Condition Cool pack
Available
Manufacturer - Targets
EGFR|||Apoptosis
Shipping Temperature
Cool pack
Storage Conditions
-20°C
Molecular Weight
1447, 61
Description
Cyclic(YCDGFYACYMDV) is a HER2 signaling pathway inhibitor with anticancer properties. In aqueous solution, Cyclic(YCDGFYACYMDV) self-assembles into nanoparticles that target HER2 on cancer cells, converting into nanofibrils. This process disrupts HER2 dimerization and subsequent downstream signaling, leading to apoptosis (Apoptosis) of cancer cells. Its inhibitory effect on HER2-positive breast cancer has been demonstrated as effective in mouse xenograft models.
Pathways
Angiogenesis|||Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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