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Autocamtide-2-related inhibitory peptide (TFA)

Autocamtide-2-related inhibitory peptide (TFA)

Item no.	CS-0062979-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Purity	>98%
Formula	C66H126N22O21F3
MWt	1611.76
Solubility	10 mM in H2O
Clinical Information	No Development Reported
Pathway	Neuronal Signaling
Target	CaMK
Biological Activity	Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC₅₀ of 40 nM. IC50 & Target: IC50: 40 nM (CaMKII)^[1]. In Vitro: It is found that Autocamtide-2-related inhibitory peptide (TFA) is a potent inhibitor of CaM-kinase II with an IC₅₀ of 40 nM, which is active in the presence or absence of Ca²⁺/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93, respectively, under the assay condition used^[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

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Delivery expected until 9/4/2025

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