Comparison

USP7/USP47 inhibitor

Item no. CS-2181-10mg
Manufacturer ChemScene
Amount 10mg
Category
Type Inhibitors
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Similar products 1247825-37-1
Available
CAS
1247825-37-1
Purity
>98%
Formula
C18H11Cl2N3O3S3
MWt
484.40
Solubility
DMSO : >= 44 mg/mL (90.83 mM)
Clinical Information
No Development Reported
Pathway
Cell Cycle/DNA Damage
Target
Deubiquitinase
Biological Activity
USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 uM and 1.0 uM, respectively. IC50 & Target: EC50: 0.42 uM (USP7), 1.0 uM (USP47)[1] In Vitro: USP7/USP47 inhibitor (compound 14) is a selective inhibitor of USP7/USP47 with EC50s of 0.42 uM and 1 uM, respectively. USP7/USP47 inhibitor does not inhibit caspase 3, calpain 1, 20S proteasome, and a panel of representative USPs (USP2, USP5, USP8, USP21, and USP28; EC50 > 31.6 uM). USP7/USP47 inhibitor inhibits the growth of HCT-116 cells with an EC50 of 7.6 uM[1].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10mg
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close