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DDR Inhibitor

DDR Inhibitor

Item no.	CS-W020277-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Oncology By Cell Type Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Similar products	1644069-80-6
Available
CAS	1644069-80-6
Purity	>98%
Formula	C23H20FN5O2
MWt	417.44
Solubility	H2O : < 0.1 mg/mL (insoluble); DMSO : 65 mg/mL (155.71 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Protein Tyrosine Kinase/RTK
Target	Discoidin Domain Receptor
Biological Activity	DDR Inhibitor is a potent discoidin domain receptor (DDR) inhibitor, with an IC₅₀ of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM. IC50 & Target: IC50: 3.3 nM (DDR2)^[1] IC53: 1.5 nM (DDR1)^[1] In Vitro: DDR Inhibitor (Example 6) is a potent DDR inhibitor, with an IC₅₀ of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM^[1].

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

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