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Afatinib (BIBW2992)

Afatinib (BIBW2992)

Item no.	DCC-DC1024-10mM
Manufacturer	DCChemicals
CASRN	439081-18-2
Amount	10 mM x 1 ml in DMSO
Quantity options	100 mg 10 mM x 1 ml in DMSO 1 g 250 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	CN(C)C\C=C\C(=O)NC1=C(OC2COCC2)C=C3C(=C1)C(=NC=N3)NC4C=C(Cl)C(F)=CC=4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Manufacturer - Applications	BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.
Molecular Weight	485, 9384

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mM x 1 ml in DMSO

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Delivery expected until 11/13/2025

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