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BMS-986260

BMS-986260

Item no.	DCC-DC65287-100mg
Manufacturer	DCChemicals
CASRN	2001559-19-7
Amount	100 mg
Quantity options	100 mg 10 mg
Category	In Vivo Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Applications	IV
Specific against	other
Smiles	ClC1=C(C([H])=C([H])C(=C1[H])C1=C(C2C([H])=C([H])C3=NC([H])=C(C#N)N3N=2)N(C([H])=N1)C([H])([H])C([H])([H])O[H])F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Manufacturer - Applications	BMS-986260 is a potent, selective, and orally bioavailable TGFβR1 inhibitor (IC50=1.6 nM). BMS-986260 demonstrated functional activity in multiple TGFβ-dependent cellular assays, excellent kinome selectivity, favorable pharmacokinetic properties, and curative in vivo efficacy in combination with anti-PD-1 antibody in murine colorectal cancer (CRC) models.
Molecular Weight	382, 7789

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 12/11/2025

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