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CPI-455

CPI-455

Item no.	DCC-DC9858-10mM
Manufacturer	DCChemicals
CASRN	1628208-23-0
Amount	10 mM x 1 mL in DMSO
Quantity options	100 mg 10 mM x 1 mL in DMSO 1 g 250 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	Cl[H].O=C1C(=C(C2C([H])=C([H])C([H])=C([H])C=2[H])N=C2C(C#N)=C([H])N([H])N12)C([H])(C([H])([H])[H])C([H])([H])[H]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Manufacturer - Applications	CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents.
Molecular Weight	314, 7695

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mM x 1 mL in DMSO

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Delivery expected until 9/4/2025

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