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KAAD-Cyclopamine

KAAD-Cyclopamine

Item no.	HY-100535-25ug
Manufacturer	MedChem Express
CASRN	306387-90-6
Amount	25 ug
Quantity options	100 mg 1 ea 25 ug 50 ug
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	96.0
Formula	C44H63N3O4
Citations	[1]Surajit Sinha, et al. Purmorphamine activates the Hedgehog pathway by targeting Smoothened. Nat Chem Biol. 2006 Jan;2(1):29-30. [2]Xiaoli Ma, et al. Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas. Carcinogenesis. 2005 Oct;26(10):1698-705.
Smiles	C[C@H]([C@@](N1CCNC(CCCCCNC(CCC2=CC=CC=C2)=O)=O)([H])[C@](C[C@H](C)C1)([H])O3)[C@@]43C(C)=C(C[C@@]5([H])[C@@]6([H])CC=C(C7)[C@@]5(CCC7=O)C)[C@@]6([H])CC4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Cyclopamine-KAAD
Shipping condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Smo
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	697.99
Product Description	KAAD-Cyclopamine, a hedgehog signaling inhibitor, is a smoothened antagonist[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 5 mg/mL (ultrasonic)
Manufacturer - Pathway	Stem Cell/Wnt
Clinical information	No Development Reported

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HY-100535-25ug-safety-datasheet.pdf