Comparison

T16Ainh-A01 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 100mg
Item no. HY-100612-100mg
CASRN 552309-42-9
Available
Product Description
T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC).
StorageTemperature
Powder -20°C 3 years; In solvent -80°C 6 months, -20°C 1 month
Formula
C19H20N4O3S2
References
[1].Fedigan S, et al. Effects of new-generation TMEM16A inhibitors on calcium-activated chloride currents in rabbit urethral interstitial cells of Cajal. Pflugers Arch. 2017 Nov; 469(11):1443-1455. | [2].Namkung W, et al. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21; 286(3):2365-74.
MolecularWeight
416.52
Research Area
Others
Solubility
DMF : ≥ 10 mg/mL (24.01 mM) | DMSO : ≥ 5 mg/mL (12.00 mM)
Target
Chloride Channel
Pathway
Membrane Transporter/Ion Channel

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 100mg
Available: In stock
available

Delivery expected until 4/20/2023 

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