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Propyl pyrazole triol

Propyl pyrazole triol

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	50mg
Item no.	HY-100689-50mg
CASRN	263717-53-9
Available
Product Description	Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%).
StorageTemperature	Powder -20°C 3 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Cancer-programmed cell death
Formula	C24H22N2O3
References	[1].Influence of cellular ERalpha/ERbeta ratio on the ERalpha-agonist induced proliferation of human T47D breast cancer cells. \| [2].Stauffer SR, et al. Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists. J Med Chem. 2000 Dec 28; 43(26):4934-47.
MolecularWeight	386.44
Research Area	Cancer
Solubility	DMSO : ≥ 100 mg/mL (258.77 mM)
Target	Estrogen Receptor/ERR
Isoform	ERα
Pathway	Others

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Amount: 50mg

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Delivery expected until 4/20/2023

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