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ZINC13466751

ZINC13466751

Item no.	HY-101028-10mg
Manufacturer	MedChem Express
CASRN	117953-17-0
Amount	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.94
Citations	[1]Xue X, et al. Discovery of novel inhibitors disrupting HIF-1α/von Hippel-Lindau interaction through shape-based screening and cascade docking. PeerJ. 2016 Dec 15;4:e2757.
Smiles	O=C(N(C1=CC=CC=C1)N=C/2C)C2=N/NC3=CC=C(N4CCOCC4)C=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	117953-17-0
Similar products	117953-17-0
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	HIF/HIF Prolyl-Hydroxylase
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, stored under nitrogen)
Molecular Weight	363.41
Product Description	ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 µM[1].
Manufacturer - Research Area	Cancer; Cardiovascular Disease
Solubility	DMSO: 20 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-101028-10mg-safety-datasheet.pdf