Comparison

SB-224289 hydrochloride European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 50mg
Item no. HY-101105A-50mg
CASRN 180084-26-8
Available
Product Description
SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect.
StorageTemperature
-20°C, stored under nitrogen; In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Applications
Neuroscience-Neuromodulation
Formula
C32H33ClN4O3
References
[1].Cassilly CD, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A. PLoS One. 2016 May 16; 11(5):e0154932. | [2].Hoplight BJ, et al. The effects of SB 224289 on anxiety and cocaine-related behaviors in a novel object task. Physiol Behav. 2005 Apr 13; 84(5):707-14. Epub 2005 Apr 13. | [3].Gaster LM, et al. The selective 5-HT1B receptor inverse agonist SB-224289, potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo. Ann N Y Acad Sci. 1998 Dec 15; 861:270-1.
MolecularWeight
557.08
Research Area
Neurological Disease
Solubility
DMSO : 14.29 mg/mL (25.65 mM; Need ultrasonic) | H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C) (insoluble)
Target
5-HT Receptor
Isoform
5-HT1B Receptor
Pathway
GPCR/G Protein; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 50mg
Available: In stock
available

Delivery expected until 4/6/2023 

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