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SB-224289 hydrochloride

SB-224289 hydrochloride

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	50mg
Item no.	HY-101105A-50mg
CASRN	180084-26-8
Available
Product Description	SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect.
StorageTemperature	-20°C, stored under nitrogen; In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Applications	Neuroscience-Neuromodulation
Formula	C32H33ClN4O3
References	[1].Cassilly CD, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A. PLoS One. 2016 May 16; 11(5):e0154932. \| [2].Hoplight BJ, et al. The effects of SB 224289 on anxiety and cocaine-related behaviors in a novel object task. Physiol Behav. 2005 Apr 13; 84(5):707-14. Epub 2005 Apr 13. \| [3].Gaster LM, et al. The selective 5-HT1B receptor inverse agonist SB-224289, potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo. Ann N Y Acad Sci. 1998 Dec 15; 861:270-1.
MolecularWeight	557.08
Research Area	Neurological Disease
Solubility	DMSO : 14.29 mg/mL (25.65 mM; Need ultrasonic) \| H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C) (insoluble)
Target	5-HT Receptor
Isoform	5-HT1B Receptor
Pathway	GPCR/G Protein; Neuronal Signaling

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Amount: 50mg

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Delivery expected until 4/6/2023

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