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L-689560

L-689560

Item no.	HY-101178-5mg
Manufacturer	MedChem Express
CASRN	139051-78-8
Amount	5 mg
Quantity options	1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.0
Citations	[1]Juan Chen, et al. A non-ionotropic activity of NMDA receptors contributes to glycine-induced neuroprotection in cerebral ischemia-reperfusion injury. 15 June 2017\|[2]Kvist T, et al. Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. J Biol Chem. 2013 Nov 15;288(46):33124-35.
Smiles	O=C([C@@H]1NC2=C(C(Cl)=CC(Cl)=C2)[C@@H](NC(NC3=CC=CC=C3)=O)C1)O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	iGluR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	380.23
Product Description	L-689560 is a potent N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. L-689560 is widely used as a radiolabeled ligand in binding studies and used for study the roles of NMDA receptors in normal neurological processes as well as in diseases[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Isoform	NMDA Receptor
Clinical information	No Development Reported

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HY-101178-5mg-safety-datasheet.pdf