TTT-28

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	5mg
Item no.	HY-101511-5mg
CASRN	1609138-51-3
Available
Product Description	TTT-28 is a synthesized thiazole-valine peptidomimetic, a novel selective inhibitor of ABCB1 (P-gp/MDR1) with high efficacy and low toxicity, which reverses the ATP-binding cassette sub-family B member 1 (ABCB1)-mediated Multidrug resistance (MDR) by selectively blocking the efflux function of ABCB1.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	Cancer-programmed cell death
Formula	C31H31N3O6S
References	[1].Wang YJ, et al. Thiazole-valine peptidomimetic (TTT-28) antagonizes multidrug resistance in vitro and in vivo by selectively inhibiting the efflux activity of ABCB1. Sci Rep. 2017 Feb 9; 7:42106.
MolecularWeight	573.66
Research Area	Cancer
Solubility	DMSO : 250 mg/mL (435.80 mM; Need ultrasonic)
Target	P-glycoprotein
Pathway	Membrane Transporter/Ion Channel

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Amount: 5mg

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Delivery expected until 4/6/2023

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