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BW 245C

BW 245C

Item no.	HY-101987-5mg
Manufacturer	MedChem Express
CASRN	72814-32-5
Amount	5 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.73
Citations	[1]Ahmad AS, et al. PGD<sub>2</sub> DP1 receptor stimulation following stroke ameliorates cerebral blood flow and outcomes. Neuroscience. 2014 Oct 24;279:260-8.\|[2]Zhang S, et al. Prostaglandin D<sub>2</sub> receptor D-type prostanoid receptor 2 mediates eosinophil trafficking into the esophagus. Dis Esophagus. 2014 Aug;27(6):601-6.\|[3]Ayabe S, et al. Prostaglandin D<sub>2</sub> inhibits collagen secretion from lung fibroblasts by activating the DP receptor. J Pharmacol Sci. 2013;121(4):312-7. Epub 2013 Mar 29.\|[4]Kobayashi K, et al. Prostaglandin D<sub>2</sub>-DP signaling promotes endothelial barrier function via the cAMP/PKA/Tiam1/Rac1 pathway. Arterioscler Thromb Vasc Biol. 2013 Mar;33(3):565-71.
Smiles	O=C(O)CCCCCC[C@@H](C(N1)=O)N(CC[C@H](C2CCCCC2)O)C1=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	72814-32-5
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Prostaglandin Receptor
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	368.47
Product Description	BW 245C is a prostanoid DP-receptor (DP1) agonist, used to treat stroke.
Manufacturer - Research Area	Cardiovascular Disease; Endocrinology
Solubility	DMSO: 50 mg/mL (ultrasonic; warming)
Manufacturer - Pathway	GPCR/G Protein
Isoform	DP
Clinical information	No Development Reported

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HY-101987-5mg-safety-datasheet.pdf