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JH-X-119-01

JH-X-119-01

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Amount	5 mg
Item no.	HY-103017A-5mg
Targets	IRAK
CASRN	2227368-54-7
eClass 6.1	32169090
eClass 9.0	32169090
Available
Product Description	JH-X-119-01 is a potent and selective interleukin-1 receptor-associated kinases 1 (IRAK1) inhibitor. JH-X-119-01 ameliorates LPS-induced sepsis in mice[1]. JH-X-119-01 inhibits IRAK1 biochemically with an apparent IC50 of 9 nM while exhibiting no inhibition of IRAK4 at concentrations up to 10 μM[2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	452.46
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Infection; Inflammation/Immunology
Solubility	DMSO : 125 mg/mL (ultrasonic)
Manufacturers Target	IRAK
Isoform	IRAK1; IRAK4
Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

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