Comparison

CRANAD-2 European Partner

Item no. HY-103242-5mg
Manufacturer MedChem Express
CASRN 1193447-34-5
Amount 5 mg
Quantity options 100 mg 10 mg 1 ea 25 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 98.0
Formula C23H25BF2N2O2
Citations [1]Ran C, et al. Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits. J Am Chem Soc. 2009 Oct 28;131(42):15257-61. <br/>[2]Ran C, et al. Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species. PLoS One. 2011 Apr 29;6(4):e19362.
Smiles CN(C)C(C=C1)=CC=C1/C=C/C2=O[B+3]([F-])([F-])O=C(/C=C/C3=CC=C(N(C)C)C=C3)[CH-]2
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Product Description
CRANAD-2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM[1][2].
StorageTemperature
4°C (Powder, protect from light)
Shipping
Room Temperature
Manufacturers Applications
Neuroscience-Neurodegeneration
MolecularWeight
410.26
Clinical Information
No Development Reported
Manufacturers Research Area
Neurological Disease
Solubility
DMSO : 2.08 mg/mL (ultrasonic; warming; heat to 60°C)
Target
Amyloid-β
Manufacturers Target
Amyloid-β
Manufacturers Pathway
Neuronal Signaling
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
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