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CRANAD-2 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 5mg
Item no. HY-103242-5mg
CASRN 1193447-34-5
Available
Product Description
CRANAD-2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM.
StorageTemperature
4°C, protect from light; In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Applications
Neuroscience-Neurodegeneration
Formula
C23H25BF2N2O2
References
[1].Ran C, et al. Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits. J Am Chem Soc. 2009 Oct 28; 131(42):15257-61. | [2].Ran C, et al. Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species. PLoS One. 2011 Apr 29; 6(4):e19362.
MolecularWeight
410.26
Research Area
Neurological Disease
Solubility
DMSO : 2.5 mg/mL (6.09 mM; ultrasonic and warming and heat to 60°C)
Target
Amyloid-β
Pathway
Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 5mg
Available: In stock
available

Delivery expected until 4/20/2023 

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