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CRANAD-2

CRANAD-2

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	5mg
Item no.	HY-103242-5mg
CASRN	1193447-34-5
Available
Product Description	CRANAD-2 is a near-infrared (NIR) Aβ plaque-specific fluorescent probe. CRANAD 2 penetrates the blood brain barrier and has a high affinity for Aβ aggregates with a Kd of 38 nM.
StorageTemperature	4°C, protect from light; In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Applications	Neuroscience-Neurodegeneration
Formula	C23H25BF2N2O2
References	[1].Ran C, et al. Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-beta deposits. J Am Chem Soc. 2009 Oct 28; 131(42):15257-61. \| [2].Ran C, et al. Non-conjugated small molecule FRET for differentiating monomers from higher molecular weight amyloid beta species. PLoS One. 2011 Apr 29; 6(4):e19362.
MolecularWeight	410.26
Research Area	Neurological Disease
Solubility	DMSO : 2.5 mg/mL (6.09 mM; ultrasonic and warming and heat to 60°C)
Target	Amyloid-β
Pathway	Neuronal Signaling

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Amount: 5mg

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Delivery expected until 4/20/2023

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