Comparison

Adaphostin European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 25 mg
Item no. HY-103275-25mg
Targets BCR
CASRN 241127-58-2
eClass 6.1 30220300
eClass 9.0 32160605
Available
Product Description
Adaphostin (NSC 680410), the adamantyl ester of AG957, is a potent p210bcr/abl inhibitor (IC50=14 μM). Adaphostin induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 ranging from 17 to 216 nM). Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells. Adaphostin increased the level of reactive oxygen species (ROS) within CLL B cells[1][2][3].
StorageTemperature
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping
Room Temperature
Manufacturers Applications
Cancer-Kinase/protease
Molecular Weight
393.48
Clinical Information
No Development Reported
Solubility
DMSO : 50 mg/mL (ultrasonic)
Pathway
Apoptosis; Protein Tyrosine Kinase/RTK
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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