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Pimonidazole

Pimonidazole

Item no.	HY-105129A-10mg
Manufacturer	MedChem Express
CASRN	70132-50-2
Amount	10 mg
Quantity options	100 mg 10 mMx1 mL 10 mg 1 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.07
Formula	C11H18N4O3
Citations	Sci Rep. 2023 Apr 21;13(1):6528. Theranostics. 2022 Apr 4;12(7):3196-3216. Asian J Pharm Sci. 2023 Mar 20. J Colloid Interface Sci. 2024 May:661:908-922. [1]Varia MA, et al. Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma. Gynecol Oncol. 1998 Nov;71(2):270-7. [2]Masaki Y, et al. Imaging Mass Spectrometry Revealed the Accumulation Characteristics of the 2-Nitroimidazole-Based Agent "Pimonidazole" in Hypoxia. PLoS One. 2016 Aug 31;11(8):e0161639.
Smiles	OC(CN1C=CN=C1[N+]([O-])=O)CN2CCCCC2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Others
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	254.29
Product Description	Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor[1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2].
Manufacturer - Research Area	Cancer
Solubility	H2O : 1 mg/mL (ultrasonic)
Manufacturer - Pathway	Others
Clinical information	Phase 2

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HY-105129A-10mg-safety-datasheet.pdf