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Xanomeline

Xanomeline

Item no.	HY-105182-50mg
Manufacturer	MedChem Express
CASRN	131986-45-3
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.52
Citations	[1]Kreir M, et al. Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons. Eur J Pharmacol. 2019;858:172474\|[2]Shekhar A, et al. Selective muscarinic receptor agonist xanomeline as a novel treatment approach for schizophrenia. Am J Psychiatry. 2008;165(8):1033-1039.\|[3]Andersen MB, et al. The muscarinic M1/M4 receptor agonist xanomeline exhibits antipsychotic-like activity in Cebus apella monkeys. Neuropsychopharmacology. 2003;28(6):1168-1175.
Smiles	CCCCCCOC1=NSN=C1C2=CCCN(C)C2
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	LY-246708
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	mAChR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	281.42
Product Description	Xanomeline, as an effective and selective muscarinic type 1 and type 4 (M1/M4) receptor agonist, increases neuronal excitability. Xanomeline can be used for the research of neurological disorders, such as schizophrenia[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 25 mg/mL (ultrasonic; warming; heat to 60°C)\|Ethanol: ≥ 100 mg/mL
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Isoform	mAChR1; mAChR4
Clinical information	Phase 4

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HY-105182-50mg-safety-datasheet.pdf