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BMS 753

BMS 753

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	25mg
Item no.	HY-107395-25mg
CASRN	215307-86-1
Available
Product Description	BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a Ki of 2 nM.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	COVID-19-immunoregulation
Formula	C21H21NO4
References	[1].M Géhin, et al. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem Biol. 1999 Aug; 6(8):519-29. \| [2].R Taneja, et al. Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RAR beta 2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts. Proc Natl Acad Sci U S A. 1996 Jun 11; 93(12): 6197-6202.
MolecularWeight	351.4
Research Area	Inflammation/Immunology
Solubility	DMSO : 50 mg/mL (142.29 mM; Need ultrasonic)
Target	RAR/RXR
Pathway	Metabolic Enzyme/Protease

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Amount: 25mg

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Delivery expected until 4/20/2023

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