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GNE 5729 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 10mg
Item no. HY-107409-10mg
CASRN 2026635-66-3
Available
Product Description
GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4.7 and 9.5 μM for GluN2C and GluN2D, respectively.
StorageTemperature
Please store the product under the recommended conditions in the Certificate of Analysis.
Applications
Neuroscience-Neurodegeneration
Formula
C17H10Cl2F3N5O
References
[1].Villemure E, et al. GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett. 2016 Oct 31; 8(1):84-89.
MolecularWeight
428.2
Research Area
Neurological Disease
Target
iGluR
Pathway
Membrane Transporter/Ion Channel; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 10mg
Available: In stock
available

Delivery expected until 4/13/2023 

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