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GNE 5729

GNE 5729

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	10mg
Item no.	HY-107409-10mg
CASRN	2026635-66-3
Available
Product Description	GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4.7 and 9.5 μM for GluN2C and GluN2D, respectively.
StorageTemperature	Please store the product under the recommended conditions in the Certificate of Analysis.
Applications	Neuroscience-Neurodegeneration
Formula	C17H10Cl2F3N5O
References	[1].Villemure E, et al. GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett. 2016 Oct 31; 8(1):84-89.
MolecularWeight	428.2
Research Area	Neurological Disease
Target	iGluR
Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling

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Amount: 10mg

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Delivery expected until 4/13/2023

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