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AEG3482

AEG3482

Item no.	HY-107599-100mg
Manufacturer	MedChem Express
CASRN	63735-71-7
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.79
Citations	[1]Salehi AH, et, al. AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 70. Chem Biol. 2006 Feb;13(2):213-23.
Smiles	O=S(C1=NN2C(S1)=NC(C3=CC=CC=C3)=C2)(N)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Targets	Apoptosis; JNK
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	280.33
Product Description	AEG3482 is a potent antiapoptotic compound that inhibits Jun kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25[1].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 250 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; MAPK/ERK Pathway
Clinical information	No Development Reported

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HY-107599-100mg-safety-datasheet.pdf